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Cruising the Mississippi River and its tributaries is an exploration of the American spirit. Gliding past the rolling farmland on Queen of the Mississippi and America, the world’s two newest paddlewheel riverboats, is an experience set in a time past and a testament to the ingenuity of the pioneers who first traveled these waters.  The fabric of the region is brought to life through our delicious regional cuisine, great onboard music, and customized excursions to historical landmarks.  Enjoy one of our themed Mississippi River cruises, perfect for music aficionados, culinary connoisseurs and history enthusiasts.

What are Mississippi River Cruises?

Upper Mississippi River Cruises sail the area between St. Louis, Missouri and St. Paul, Minnesota.  Lower Mississippi River Cruises sail from Memphis, Tennessee and New Orleans, Louisiana. In addition to cruises directly on Mississippi River, there are also cruises that cruise its tributaries including the Ohio, and Tennessee Rivers.  

Mississippi River Cruises

Complimentary Pre-Cruise Hotel

Pre-Cruise Hotel Package

Plus Save $400 when you reserve 9 months in advance
Call 800.460.4518 for additional details.


The American Cruise Lines Difference

Historic Destinations
Historic Destinations
Delicious Cuisine
Gracious Service
Nightly Entertainment